Self-assembled levan nanoparticles for targeted breast cancer imaging.

Targeted detection of the cancer cells using the anti-CD24 bio modified PEGylated gold nanoparticles: the application of CD24 as a vital cancer biomarker

Objective(s): The central role of molecular imaging modalities in cancer management is an undeniable fact that could help to diagnose cancer tumors in early stages. The main aim of this study is to prepare a novel targeted molecular imaging nanoprobe of CD24-PEGylated Au NPs to improve the ability of Computed tomography scanning (CT scan) outputs for both in vitro and in vivo detection of breas...

Folic acid-modified diatrizoic acid-linked dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human cervical cancer

In vitro Study of SPIONs-C595 as Molecular Imaging Probe for Specific Breast Cancer (MCF-7) Cells Detection

Background: Magnetic resonance imaging (MRI) plays an essential role in molecular imaging by delivering the contrast agent into targeted cancer cells. The aim of this study was to evaluate the C595 monoclonal antibody-conjugated superparamagnetic iron oxide nanoparticles (SPIONs-C595) for the detection of breast cancer cell (MCF-7). Methods: The conjugation of monoclonal antibody and nanopartic...

مقایسه اثر سمیت سلولی نانوذرات کیتوزان- دوسه تاکسل و داروی آزاد دوسه تاکسل بر روی سلول های سرطانی سینه MDA-MB-231

Background and objective: Resulting in the accumulation of somatic mutations in cancer cells caused. Breast cancer is the most commonly diagnosed cancer among women worldwide. The use of nanoscale drug delivery systems is important for effective treatment. The main aim of this study was to determine effects of chitosan conjugated to docetaxel nanoparticles in treatment of breast cancer. Methods...

Targeted MRI for Breast Cancer using Iron Oxide Nanoparticles

Magnetic Resonance Imaging (MRI) utilizes a powerful magnetic field to align the nuclear magnetization of hydrogen atoms in water in the body without the use of ionizing radiation. Iron oxide (IO) nanoparticles are the only FDA approved nanoparticles used as a MRI contrast agent. Paramagnetic IO nanoparticles can induce remarkably strong magnetic resonance imaging contrast and have a large surf...